What’s stem cell?

In the term "stem cells", "stem" means "tree", "the trunk of a tree" and "origin". Stem cells just like trees that can sprout branches and leaves, blossom and fruit. Therefore, scientists define stem cells as follows: stem cell is a primitive cell possesses self-renewal capacity and multiple-differentiation potential. It is the original cell of an organism. Stem cells have been called "multifunctional cells" by medical circle as they can differentiate into a variety of functioning cells and histoorgans under certain conditions. Stem cells are a class of undifferentiated cells that are able to differentiate into specialized cell types.

Commonly, stem cells come from two main sources: embryos which are formed during the Blastocyst phase of embryological development (embryonic stem cells), and adult tissue (adult stem cells). Both types are generally characterised by their potency or potential to differentiate into different cell types, such as skin, muscle or bone.

Stem Cell Transportation

What’s stem cells regeneration?

Stem cells regeneration means adopting autologous stem cells for implantation. Where there is sickness, stem cells will be implanted there to cure illnesses, so to speak.

How does stem cells regeneration work?

The conception of regenerative medicine derives from leech, newt, house lizard and some other animals. These animals not only have powerful regenerative stem cells, but also possess mechanisms that can start the growth of stem cells rapidly, so that they can grow new tails and limbs soon after broken.

Stem cells technology is part of "regenerative medicine technology". The greatest value of stem cells technology is that it can produce whole new, younger and normal cells, tissues, organs and so forth by stem cells isolation, culture and directional induced differentiation in vitro. Then implant them into human body via specific implantation technology to replace those natural or pathological dead cells. This technology brings an epoch-making revolution for treating varied intractable diseases(take hepatic cirrhosis for example).

Sources of stem cells for implantation

There are 3 possible sources of stem cells to use for transplants: bone marrow, the bloodstream (peripheral blood), and umbilical cord blood from newborns. Although bone marrow was the first source used in stem cell transplant, peripheral blood is used most often today.

Stem cells implantation procedure of Modern Cancer Hospital Guangzhou:

  • Step1:Take marrow from patient;
  • Step2:Isolate, purify and multiply stem cells in vitro;
  • Step3:Transfuse stem cells suspension back to patient’s liver;
  • Step4:Stem cells settle in the liver and differentiate into hepatic cells.

Determining factors of effect of stem cells implantation:

1. Qualitative factor of stem cells. The treatment of simply isolating patient’s peripheral blood stem cells and bone marrow stem cells then transfusing them into patient’s body can not achieve a very good effect. The stem cells we use are isolated and cultured with specific technology by Modern Cancer Hospital Guangzhou.

2. Input means. We apply hepatic artery interventional therapy. Currently, portal vein input method, intravenous infusion and transhepatic implantation are used internationally. However, we believe hepatic artery interventional therapy is the best input means since hepatic artery is the nutrition-supplying artery.

3. Treatment circle. We believe treatment circle should be based on patient’s specific conditions. Efficient treatment and less spending are things we should consider for patients.

Clinical applications

Currently, stem cells implantation are internationally used for treating type 1 and type 2 diabetes, diabetic foot, hepatocirrhosis, serious disease of the liver, nephrotic syndrome, lupus nephritis, femoral head necrosis, myasthenia gravis, masculine sexual dysfunction and peripheral vascular diseases, which are very hard to be treated via conventional therapies.

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